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  4. Recombinant Human Calcitonin gene-related peptide 2 (CALCB)

Recombinant Human Calcitonin gene-related peptide 2 (CALCB)

In Stock
  • 货号：
    CSB-EP004435HU
  • 规格：
    ￥1344
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    CALCB
  • Uniprot No.：
  • 别名：
    Beta type CGRP; Beta-CGRP; Beta-type CGRP; CALC2; Calcb; CALCB_HUMAN; Calcitonin gene related peptide 2; Calcitonin gene related peptide II; Calcitonin gene-related peptide 2; Calcitonin gene-related peptide II; Calcitonin related polypeptide; beta; CGRP II; CGRP-II; CGRP2; CGRPII; FLJ30166
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length
  • 来源：
    E.coli
  • 分子量：
    40.7kDa
  • 表达区域：
    1-127aa
  • 氨基酸序列
    MGFRKFSPFLALSILVLYQAGSLQAAPFRSALESSPDPATLSKEDARLLLAALVQDYVQMKASELKQEQETQGSSSAAQKRACNTATCVTHRLAGLLSRSGGMVKSNFVPTNVGSKAFGRRRRDLQA
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal GST-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.
  • 基因功能参考文献：
    1. The results suggest that C12orf39, CSTA, and CALCB are novel ATF4 target genes, and that C12orf39 promoter activity is activated by ATF4 through amino acid response element. PMID: 26967115
    2. Keratinocyte-derived CGRPbeta may modulate epidermal homeostasis through autocrine/paracrine signaling and may contribute to chronic pain under pathological conditions. PMID: 21641113
    3. Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells. PMID: 19192276
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Calcitonin family
  • 数据库链接：

    HGNC: 1438

    OMIM: 114160

    KEGG: hsa:797

    STRING: 9606.ENSP00000346017

    UniGene: Hs.534305