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  4. Recombinant Danio rerio Forkhead box protein H1 (foxh1)

Recombinant Danio rerio Forkhead box protein H1 (foxh1)

  • 中文名称：
    斑马鱼foxh1重组蛋白
  • 货号：
    CSB-YP878004DIL
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    斑马鱼foxh1重组蛋白
  • 货号：
    CSB-EP878004DIL
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    斑马鱼foxh1重组蛋白
  • 货号：
    CSB-EP878004DIL-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    斑马鱼foxh1重组蛋白
  • 货号：
    CSB-BP878004DIL
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    斑马鱼foxh1重组蛋白
  • 货号：
    CSB-MP878004DIL
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    foxh1
  • Uniprot No.：
  • 别名：
    foxh1; fast1; surForkhead box protein H1; Forkhead activin signal transducer 1; Fast-1; Schmalspur protein
  • 种属：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-472
  • 氨基酸序列
    MTKHWGGPGL LAPPVITVGE GAQRDHHLDC RIGYSSSKRS CHRSSNPLLE LGGRLDKSTG MAQDSCYRAK ATNQGPWELQ DGNSSGGKKK NYQRYPKPPY SYLAMIAMVI QNSPEKKLTL SEILKEISTL FPFFKGNYKG WRDSVRHNLS SYDCFVKVLK DPGKPQGKGN FWTVEVNRIP LELLKRQNTA VSRQDETIFA QDLAPYIFQG YSQPNKSKPL PPESSLPPVP TRQSPPPSED PYRPKLDSTF AIDSLLHSLR PASSAGEGLR ERESWGVGPP PHTRSTTPPR PCNASYNGSS SASSVSPASD FSDEDWRGVT VVGKRSGDRG ITSDAYSDSC PPPNKSSKRG NTPPWELPTS YAKYTPPNAV APPSMRFNGN PFMPLGGIPF YGYGGAHVTT SHLIGHPYWP ILPSGPVSIQ APPLLMDLDS MLQSVPPNKS VFDALGSNNQ TVHPSPNQYA LQNGPSLCKY SL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcriptional activator. Activates an activin response element (ARE). Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Modulator of nodal signaling required for organizer formation. Also required for the development of dorsal axial structures and left-right symmetry.
  • 基因功能参考文献：
    1. Axial mesoderm induction is differentially disrupted in FoxH1 mutants. FoxH1 mutants respond differently to Activin-like signaling. PMID: 21637786
    2. These results and the association of FoxH1 and Mixer/Bon with phosphorylated Smad2 support a role for these factors as components of the Nodal signaling pathway. PMID: 14522874
    3. flk1 is a direct target of FoxH1; FoxH1 is involved in vessel formation in zebrafish. PMID: 17306248
    4. to an essential role for maternal FoxH1 and downstream keratins during gastrulation that is epistatic to Nodal signaling PMID: 17719025
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    KEGG: dre:57930

    STRING: 7955.ENSDARP00000072485

    UniGene: Dr.7743