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  4. Recombinant Bovine Doublesex and mab-3 related transcription factor 1 (DMRT1)

Recombinant Bovine Doublesex and mab-3 related transcription factor 1 (DMRT1)

  • 中文名称：
    牛DMRT1重组蛋白
  • 货号：
    CSB-YP006969BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    牛DMRT1重组蛋白
  • 货号：
    CSB-EP006969BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    牛DMRT1重组蛋白
  • 货号：
    CSB-EP006969BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    牛DMRT1重组蛋白
  • 货号：
    CSB-BP006969BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    牛DMRT1重组蛋白
  • 货号：
    CSB-MP006969BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    DMRT1
  • Uniprot No.：
  • 别名：
    DMRT1Doublesex and mab-3 related transcription factor 1
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-357
  • 氨基酸序列
    MPNDDAYSKP SAPSEAPQTP GAPPQGKAGG GGGGSGSDSG ASGTGAVSGK KSPRLPKCAR CRNHGYASPL KGHKRFCMWR DCQCKKCNLI AERQRVMAAQ VALRRQQAQE EELGISHPIP LPSTAELMVK RENSSGNPCL MIESSSSSQP PPASTPSTAA PGPEGRMVIQ DIPAVTSRGH VENTPDLVSD STYYSSFYQP SLFPYYNNLY NYPQYPMALA ADSSSGDVGN PLGGSPVKNS LRSLPAPYVP GQTGNQWQMK NSENRHAVSS QYRMHSYYPP PSYLGQSMSQ IFTFEDSASY SEAKASAFSP PSSQDSGLVS LPSSSPIGNE STKAVLDCES ASEPSNFAVA PIIEEDE
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis.
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    DMRT family
  • 数据库链接：

    KEGG: bta:616245

    STRING: 9913.ENSBTAP00000023667

    UniGene: Bt.50653