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  4. Recombinant Bordetella pertussis Pertactin autotransporter (prn), partial

Recombinant Bordetella pertussis Pertactin autotransporter (prn), partial

In Stock
  • 货号：
    CSB-EP321224BUA
  • 规格：
    ￥2328
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    prn
  • Uniprot No.：
  • 别名：
    prn; omp69A; BP1054; Pertactin autotransporter; P.93) [Cleaved into: Outer membrane protein P.69; Pertactin translocator]
  • 种属：
    Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
  • 蛋白长度：
    Partial
  • 来源：
    E.coli
  • 分子量：
    45.8kDa
  • 表达区域：
    632-910aa
  • 氨基酸序列
    ALSKRLGELRLNPDAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGYATYIADSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGRRFTHADGWFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRGHSLYASYEYSKGPKLAMPWTFHAGYRYSW
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-SUMO-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Agglutinogen that binds to eukaryotic cells; a process mediated by the R-G-D sequence. Pertactin may have a role in bacterial adhesion, and thus play a role in virulence. May contribute to the disease state of whooping cough.
  • 基因功能参考文献：
    1. Prn-KO strains induced an increased production of pro-inflammatory cytokines by human and murine dendritic cell. PMID: 29559630
    2. Multiple driving forces required for efficient secretion of autotransporter virulence proteins, such as pertactin. PMID: 25670852
    3. Results indicate that the purified pertactin is a potential candidate as immunogen for preparation of diagnostic reagents and as a vaccine component. PMID: 20306653
  • 亚细胞定位：
    [Pertactin autotransporter]: Periplasm.; [Outer membrane protein P.69]: Secreted. Cell surface.; [Pertactin translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
  • 数据库链接：

    KEGG: bpe:BP1054

    STRING: 257313.BP1054