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sulA Antibody

  • 货号：
    CSB-PA365383LA01ENV
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Escherichia coli sulA Polyclonal antibody
  • Uniprot No.：
    P0AFZ5
  • 基因名：
    sulA
  • 别名：
    sulA antibody; sfiA antibody; b0958 antibody; JW0941 antibody; Cell division inhibitor SulA antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Escherichia coli
  • 免疫原：
    Recombinant Escherichia coli Cell division inhibitor SulA protein (1-169AA)
  • 免疫原种属：
    Escherichia coli
  • 标记方式：
    Non-conjugated

    本页面中的产品，sulA Antibody (CSB-PA365383LA01ENV)，的标记方式是Non-conjugated。对于sulA Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA365383LB01ENV sulA Antibody, HRP conjugated ELISA
    FITC CSB-PA365383LC01ENV sulA Antibody, FITC conjugated
    Biotin CSB-PA365383LD01ENV sulA Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. The effect of overexpression of SulA is neutralized by antitoxin CbeA (yeeU).
  • 基因功能参考文献：
    1. In current work the recovery of division process of Escherichia coli cells after division arrest due to expression of SOS-response protein SulA was studied. Data indicate that cells are able to rapidly restore normal division; also nucleoid occlusion seems to be the main septum positioning mechanism during the process. PMID: 30188109
    2. results indicate existence of a SulA-dependent pathway of high-pressure-induced cell filamentation and suggest involvement of the SOS response, and particularly of SulA, in high-pressure-mediated cell death in strains which are compromised in Lon function PMID: 15748989
    3. Results found that the binding of SulA to FtsZ is necessary but not sufficient for inhibition of FtsZ polymerization. PMID: 18245292
  • 蛋白家族：
    SulA family
  • 数据库链接：

    KEGG: ecj:JW0941

    STRING: 316385.ECDH10B_1028