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pvdA Antibody

  • 货号：
    CSB-PA706553HA01EZX
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: pvdA antibody at 2.8µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 65 kDa
      Observed band size: 65 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Pseudomonas aeruginosa pvdA Polyclonal antibody
  • Uniprot No.：
    Q51548
  • 基因名：
    pvdA
  • 别名：
    pvdA antibody; pvd-1 antibody; PA2386 antibody; L-ornithine N(5)-monooxygenase antibody; EC 1.14.13.195 antibody; L-ornithine N(5)-hydroxylase antibody; Ornithine hydroxylase antibody; L-ornithine N(5)-oxygenase antibody; Pyoverdin biosynthesis protein A antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Pseudomonas aeruginosa
  • 免疫原：
    Recombinant Pseudomonas aeruginosa L-ornithine N(5)-monooxygenase protein (1-443AA)
  • 免疫原种属：
    Pseudomonas aeruginosa
  • 标记方式：
    Non-conjugated

    本页面中的产品，pvdA Antibody (CSB-PA706553HA01EZX)，的标记方式是Non-conjugated。对于pvdA Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA706553HB01EZX pvdA Antibody, HRP conjugated ELISA
    FITC CSB-PA706553HC01EZX pvdA Antibody, FITC conjugated
    Biotin CSB-PA706553HD01EZX pvdA Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the conversion of L-ornithine to N(5)-hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr-L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate.
  • 基因功能参考文献：
    1. PvdA is a membrane-associated protein located at the old cell pole PMID: 22498339
    2. The first two structures of a class B N-hydroxylating monooxygenase were determined with FAD in oxidized (1.9 A resolution) and reduced (3.03 A resolution) states PMID: 21757711
    3. overexpression and purification of active recombinant L-ornithine N5-hydroxylase, PvdA; detailed steady-state kinetic analysis to determine the substrate and coenzyme specificities PMID: 17015659
    4. The membrane topogenic determinants of PvdA were studies, and PvdA appears to have a single N-terminal domain anchored to the inner membrane. PMID: 18757814
    5. PvdA employs a kinetic mechanism that is a hybrid of those previously documented for other flavin-dependent hydroxylases PMID: 19368334

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  • 亚细胞定位：
    Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family
  • 数据库链接：

    KEGG: pae:PA2386

    STRING: 208964.PA2386