Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. oprF Antibody

oprF Antibody

  • 货号：
    CSB-PA318417LA01EZX
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: oprF antibody at 5μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 39.3 kDa
      Observed band size: 44 kDa
  • 其他：

产品详情

  • 产品描述：

    The OprF polyclonal antibody is a rabbit antibody that specifically recognizes Pseudomonas aeruginosa OprF protein. Its immunogen is the recombinant Pseudomonas aeruginosa OprF protein (25-350aa). It has been validated for use in ELISA and WB assays. The antibody has been purified using protein G and has a purity level of over 95%.

    OprF is one of the major porins in the outer membrane of P. aeruginosa, participating in the uptake of nutrients and antibiotics, as well as in the efflux of toxins and metabolic waste products. It has also been implicated in virulence and pathogenesis in P. aeruginosa.

  • 产品名称：
    Rabbit anti-Pseudomonas aeruginosa oprF Polyclonal antibody
  • Uniprot No.：
    P13794
  • 基因名：
    oprF
  • 别名：
    oprF antibody; PA1777 antibody; Outer membrane porin F antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Pseudomonas aeruginosa
  • 免疫原：
    Recombinant Pseudomonas aeruginosa Outer membrane porin F protein (25-350AA)
  • 免疫原种属：
    Pseudomonas aeruginosa
  • 标记方式：
    Non-conjugated

    本页面中的产品，oprF Antibody (CSB-PA318417LA01EZX)，的标记方式是Non-conjugated。对于oprF Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA318417LB01EZX oprF Antibody, HRP conjugated ELISA
    FITC CSB-PA318417LC01EZX oprF Antibody, FITC conjugated
    Biotin CSB-PA318417LD01EZX oprF Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium.
  • 基因功能参考文献：
    1. OprF (an outer membrane porin, highly conserved in the Pseudomonas) binds human C3b. PMID: 25964476
    2. LecB binds to the outer membrane protein OprF PMID: 23056489
    3. oprF transcription was increased in response to low NaCl or high sucrose concentrations, and this induced transcription was strongly impaired in the absence of SigX. PMID: 22685281
    4. Prevention of disulfide bond formation in OprF increases its pore-forming activity. PMID: 20978537
    5. This is the first study showing a link between OprF, PQS synthesis, T3SS, and virulence factor production PMID: 21189321
    6. Data show that the recombinant plasmid pIRES-tPA-OprF-MyD88 has been successfully constructed and tPA-OprF and MyD88 protein can be highly expressed in transfected cells. PMID: 19257978
    7. findings suggest that OprF could adopt two alternative conformations in the outer membrane and that folding is thermoregulated PMID: 15528532
    8. findings demonstrate that interferon-gamma binds to an outer membrane protein in Pseudomonas aeruginosa, OprF, resulting in the expression of a quorum-sensing dependent virulence determinant, the PA-I lectin PMID: 16051797
    9. analysis of OprF from Pseudomonas aeruginosa PMID: 16397890
    10. OprF exists in two different conformations PMID: 16595653
    11. analysis of Pseudomonas aeruginosa porin OprF PMID: 16617058
    12. Major outer membrane protein F (OprF) is identified as a protein with important functions; mutant Pseudomonas aeruginosa deficient in OprF negates the antibacterial role of host neutrophil elastase both in vitro and in a pneumonia model. PMID: 18802098

    显示更多

    收起更多

  • 亚细胞定位：
    Cell outer membrane; Multi-pass membrane protein.
  • 蛋白家族：
    OmpA family
  • 数据库链接：

    KEGG: pae:PA1777

    STRING: 208964.PA1777