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lptA Antibody

  • 货号：
    CSB-PA360010HA01ENV
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Escherichia coli lptA Polyclonal antibody
  • Uniprot No.：
    P0ADV1
  • 基因名：
    lptA
  • 别名：
    lptA antibody; yhbN antibody; b3200 antibody; JW3167 antibody; Lipopolysaccharide export system protein LptA antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Escherichia coli
  • 免疫原：
    Recombinant Escherichia coli Lipopolysaccharide export system protein LptA protein (28-185AA)
  • 免疫原种属：
    Escherichia coli
  • 标记方式：
    Non-conjugated

    本页面中的产品，lptA Antibody (CSB-PA360010HA01ENV)，的标记方式是Non-conjugated。对于lptA Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA360010HB01ENV lptA Antibody, HRP conjugated ELISA
    FITC CSB-PA360010HC01ENV lptA Antibody, FITC conjugated
    Biotin CSB-PA360010HD01ENV lptA Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
  • 基因功能参考文献：
    1. characterization of a viable quadruple lptA mutant impaired in the assembly of the Lpt machinery, although it retains the ability to bind LPS; although viable, the quadruple lptA mutant disrupts outer membrane (OM) asymmetry and severely impairs the OM permeability barrier; analysis of 2 independent suppressors revealed different strategies adopted by the cell to overcome defects in LPS biogenesis PMID: 29109183
    2. LptA molecular structure is affected by lipopolysaccharides binding. PMID: 28419595
    3. An induced folding process characterizes the partial-loss of function mutant LptAI36D in its interactions with lipopolysaccharide constituent ligands. PMID: 26123264
    4. Studied the assembly and architecture of LptA oligomers. PMID: 23897621
    5. results suggest that LptA operate in the LPS assembly pathway and, together with other as-yet-unidentified components, could be part of a complex devoted to the transport of LPS from the periplasmic surface of the IM to the OM. PMID: 18424520
    6. LptA binds structurally diverse lipopolysaccharide (LPS) substrates in vitro and demonstrate that it interacts specifically with the lipid A domain of LPS PMID: 18480051

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  • 亚细胞定位：
    Periplasm. Note=Associates with both the inner membrane and the outer membrane.
  • 蛋白家族：
    LptA family
  • 数据库链接：

    KEGG: ecj:JW3167

    STRING: 316385.ECDH10B_3374