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lktA Antibody

  • 中文名称：
    lktA兔多克隆抗体
  • 货号：
    CSB-PA314743EA01ESE
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品描述：

    CUSABIO produced the polyclonal antibody against lktA by immunizing rabbits with a synthetic peptide that corresponds to amino acids 715-953 of the recombinant Leukotoxin protein. The antiserum obtained from the rabbits was purified using protein G affinity chromatography, resulting in a purity level of 95% for the anti-lktA antibody.

    This antibody is an unconjugated IgG that specifically reacts with Escherichia coli lktA. LktA is a virulence factor generated by the bacterium Mannheimia haemolytica, which targets and kills immune cells, particularly leukocytes, in the lungs of infected animals. The lktA polyclonal antibody developed by CUSABIO is suitable for detecting the lktA protein in ELISA.

  • 产品名称：
    Rabbit anti-Mannheimia haemolytica lktA Polyclonal antibody
  • Uniprot No.：
    P0C085
  • 基因名：
    lktA
  • 别名：
    lktA antibody; Leukotoxin antibody; Lkt antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Mannheimia haemolytica
  • 免疫原：
    Recombinant Mannheimia haemolytica Leukotoxin protein (715-953AA)
  • 免疫原种属：
    Mannheimia haemolytica
  • 标记方式：
    Non-conjugated

    本页面中的产品，lktA Antibody (CSB-PA314743EA01ESE)，的标记方式是Non-conjugated。对于lktA Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA314743EB01ESE lktA Antibody, HRP conjugated ELISA
    FITC CSB-PA314743EC01ESE lktA Antibody, FITC conjugated
    Biotin CSB-PA314743ED01ESE lktA Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Pasteurella leukotoxins are exotoxins that attack host leukocytes and especially polymorphonuclear cells, by causing cell rupture. The leukotoxin binds to the host LFA-1 integrin and induces a signaling cascade leading to many biological effects, including tyrosine phosphorylation of the CD18 tail, elevation of the intracellular Ca(2+) and lysis of the host cell. This leukotoxin is a major contributor to the pathogenesis of lung injury in ovine pneumonic pasteurellosis. It has also weak hemolytic activity.
  • 亚细胞定位：
    Secreted. Host cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    RTX prokaryotic toxin (TC 1.C.11) family