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ipaC Antibody

  • 货号：
    CSB-PA324678ZA01SZB
  • 规格：
    ￥880
  • 图片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes:ipaC Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 46.2 kDa
      Observed band size: 47 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Shigella flexneri ipaC Antibody Polyclonal antibody
  • Uniprot No.：
    P18012
  • 基因名：
    ipaC Antibody
  • 别名：
    Invasin IpaC (42 kDa antigen), ipaC
  • 宿主：
    Rabbit
  • 反应种属：
    Shigella flexneri
  • 免疫原：
    Recombinant Shigella flexneri ipaC protein (1-363aa)
  • 免疫原种属：
    Shigella flexneri
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Forms a pore with IpaB, which is inserted into host cell membrane through the Mxi/Spa apparatus, during cell contact. This pore probably allows the translocation of IpaA. The C-terminus of IpaC could be involved in actin polymerization that leads to the cell extension formation and its N-terminus could be involved in the conversion of filopodial extensions into lamellipodial extension. Most extensions results from Cdc42 activation by IpaC whereas the lamellipodial extensions result from the Rac activation by Cdc42.
  • 亚细胞定位：
    Secreted. Note=Secreted through the specialized type-III secretion system Mxi/Spa. Inserted into the host cell membrane.
  • 蛋白家族：
    Invasin protein C family
  • 数据库链接：

    KEGG: sfl:CP0127