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fgf3 Antibody

  • 货号：
    CSB-PA008630LA01DIL
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) fgf3 Polyclonal antibody
  • Uniprot No.：
    P48802
  • 基因名：
  • 别名：
    fgf3 antibody; fgf-3Fibroblast growth factor 3 antibody; FGF-3 antibody; Heparin-binding growth factor 3 antibody; HBGF-3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Zebrafish
  • 免疫原：
    Recombinant Zebrafish Fibroblast growth factor 3 protein (19-256AA)
  • 免疫原种属：
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 标记方式：
    Non-conjugated

    本页面中的产品，fgf3 Antibody (CSB-PA008630LA01DIL)，的标记方式是Non-conjugated。对于fgf3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA008630LB01DIL fgf3 Antibody, HRP conjugated ELISA
    FITC CSB-PA008630LC01DIL fgf3 Antibody, FITC conjugated
    Biotin CSB-PA008630LD01DIL fgf3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation.
  • 基因功能参考文献：
    1. Pharmacological inhibition of FGF signaling or a mutation in the fgf3 gene can compensate the gain of caudal hypothalamic dopaminergic neurons in cnot8m1061 mutants, indicating a role for Fgf3 in control of development of this dopaminergic population PMID: 25478689
    2. Fgf10b participates in a late phase of otic induction and, in combination with fgf3, is especially critical for epibranchial induction. PMID: 24677486
    3. Fgf3 and Fgf10a work in concert to promote maturation of the epibranchial placodes in zebrafish. PMID: 24358375
    4. Myogenic factor (Myf)5 modulates craniofacial cartilage development through the fgf3 signaling pathway. PMID: 23992145
    5. Data indicate that foxi1 is expressed in branchial arch ectoderm and endoderm, and morpholino knock-down of foxi1 causes apoptosis of neural crest in the branchial arches, which is rescued by fgf3. PMID: 24650709
    6. Fgf10 and Fgf3 secreted from the forming neurohypophysis exert direct guidance effects on hypothalamic neurosecretory axons. PMID: 23404108
    7. In lia(-/-) (fgf3(-/-)) mutants, anterior otic character is reduced, but not lost altogether. PMID: 21831919
    8. Requirement for endoderm and FGF3 in ventral head skeleton formation PMID: 12223404
    9. Results show that fibroblast growth factor 3 signaling from the ventral diencephalon is required to induce the expression of lim3, pit1 and other pituitary-specific genes in the underlying adenohypophyseal progenitor cells. PMID: 15229178
    10. Results suggest that Fgf3 is a major endodermal determinant required for epibranchial placode neurogenesis. PMID: 16077091
    11. fgf3 can act as otic inducers PMID: 17239227
    12. The FGF3 signal delineates the melanotrope and corticotrope lineage boundary, contributing to establishment of the pituitary pars distalis and pars intermedia. PMID: 18514643
    13. rosettes form cyclically from a progenitor pool at the leading zone of the posterior lateral line primordium as neuromasts are deposited from trailing region; fgf3/10 signals localized to leading zone required for rosette formation & primordium migration PMID: 18583612
    14. morphogenetic tissue rearrangements during eye evagination result in progenitor cells in the nasal half of the retina primordium being brought into proximity to the sources of three fibroblast growth factors, Fgf8/3/24, outside the eye. PMID: 19823566

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Heparin-binding growth factors family
  • 数据库链接：

    KEGG: dre:30549

    STRING: 7955.ENSDARP00000099184

    UniGene: Dr.83293