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deoD Antibody

  • 货号：
    CSB-PA18357A0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: deoD antibody at 2µg/ml + DH5a whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 26 kDa
      Observed band size: 26 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Escherichia coli deoD Polyclonal antibody
  • Uniprot No.：
    P0ABP8
  • 基因名：
    deoD
  • 别名：
    deoD antibody; pup antibody; b4384 antibody; JW4347 antibody; Purine nucleoside phosphorylase DeoD-type antibody; PNP antibody; EC 2.4.2.1 antibody; Inosine phosphorylase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Escherichia coli
  • 免疫原：
    Recombinant Escherichia coli Purine nucleoside phosphorylase DeoD-type protein (2-239AA)
  • 免疫原种属：
    Escherichia coli
  • 标记方式：
    Non-conjugated

    本页面中的产品，deoD Antibody (CSB-PA18357A0Rb)，的标记方式是Non-conjugated。对于deoD Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA18357B0Rb deoD Antibody, HRP conjugated ELISA
    FITC CSB-PA18357C0Rb deoD Antibody, FITC conjugated
    Biotin CSB-PA18357D0Rb deoD Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Acts on 6-amino and 6-oxopurines including deoxyinosine, deoxyguanosine, deoxyadenosine, adenosine, guanosine, and inosine. Does not act on xanthosine. May also catalyze a phosphate-dependent transfer of the pentose moiety from one purine base to another.
  • 基因功能参考文献：
    1. These studies also indicate an important role of the phenyl ring of Phe159 for FRET in the wild-type purine nucleoside phosphorylase, which does not exist in the Ala159 mutant, and for the effective association of PNP with formycin A . PMID: 25754135
    2. Data suggest that in active sites of purine nucleoside phosphorylase complexed with phosphate and formycin A, recombinant enzyme exhibits unexpected binding site for phosphate and exhibits stoichiometry of two phosphate molecules per enzyme subunit. PMID: 22569248
    3. The deoD gene was cloned from Escherichia coli MG1665 & overexpressed in E. coli BL 21(DE3). PMID: 22113014
    4. in solution similar to the crystal, E. coli PNP is a hexameric molecule and previous suggestions for coexistence of two oligomeric forms are incorrect. PMID: 16751611
    5. Role of ionization of the phosphate cosubstrate on phosphorolysis by purine nucleoside phosphorylase (PNP) PMID: 17639373

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  • 蛋白家族：
    PNP/UDP phosphorylase family
  • 数据库链接：

    KEGG: ecj:JW4347

    STRING: 316385.ECDH10B_4542