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ZXDC Antibody

  • 货号：
    CSB-PA027161GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q2QGD7
  • 基因名：
    ZXDC
  • 别名：
    ZXDC antibody; ZXDL antibody; Zinc finger protein ZXDC antibody; ZXD-like zinc finger protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human ZXDC
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
  • 基因功能参考文献：
    1. Data show that ZXDC1 is a regulator in the process of myeloid function and that ZXDC1 is responsible for Ccl2 gene de-repression by BCL6. PMID: 23954399
    2. Role of ZXD proteins in regulating MHC II transcription. PMID: 19777325
    3. ZXDC is an important regulator of both MHC class I and class II transcription PMID: 16600381
    4. ZXDA and ZXDC form an important regulatory complex for MHC II gene transcription. PMID: 17493635
    5. study found sumoylation does not appear to disrupt or modulate interaction of ZXDC with binding partners; sumoylation of ZXDC is required for full activity of transcriptional activation domain; study suggests sumoylation is an important regulator of ZXDC PMID: 17696781

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    ZXD family
  • 组织特异性：
    Expressed at high levels in heart, kidney, liver and testis, at moderate levels in brain and stomach, and at low levels in lung, muscle, placenta, small intestine and spleen.
  • 数据库链接：

    HGNC: 28160

    OMIM: 615746

    KEGG: hsa:79364

    STRING: 9606.ENSP00000374359

    UniGene: Hs.440049