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ZNHIT1 Antibody

  • 货号：
    CSB-PA004613
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HuvEc cells using ZNHIT1 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    O43257
  • 基因名：
    ZNHIT1
  • 别名：
    ZNHIT1 antibody; CGBP1 antibody; ZNFN4A1 antibody; Zinc finger HIT domain-containing protein 1 antibody; Cyclin-G1-binding protein 1 antibody; Zinc finger protein subfamily 4A member 1 antibody; p18 Hamlet antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ZNHIT1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Seems to play a role in p53-mediated apoptosis induction. Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity.
  • 基因功能参考文献：
    1. p18(Hamlet) is a new cell-fate regulator that links the p38 MAPK and p53 pathways and contributes to the establishment of p53-regulated stress responses. PMID: 17380123
    2. Study reports that p18(Hamlet) can also mediate the cell cycle arrest induced in response to gamma-irradiation, by participating in the p53-dependent upregulation of the cell cycle inhibitor p21(Cip1) (CDKN1A). PMID: 17700068
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    ZNHIT1 family
  • 组织特异性：
    Expressed abundantly in liver, but weakly in skeletal muscle, ovary and small intestine.
  • 数据库链接：

    HGNC: 21688

    KEGG: hsa:10467

    STRING: 9606.ENSP00000304593

    UniGene: Hs.211079