ZNF638 Antibody
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货号:CSB-PA003469
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规格:¥880
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图片:
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其他:
产品详情
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Uniprot No.:Q14966
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基因名:ZNF638
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别名:CTCL tumor antigen se33 1 antibody; CTCL-associated antigen se33-1 antibody; Cutaneous T cell lymphoma associated antigen se33 1 antibody; Cutaneous T-cell lymphoma-associated antigen se33-1 antibody; DKFZp686P1231 antibody; MGC26130 antibody; MGC90196 antibody; NP220 antibody; NP220 nuclear protein antibody; Nuclear protein 220 antibody; ZFML antibody; Zfp638 antibody; Zinc finger matrin like antibody; Zinc finger matrin like protein antibody; Zinc finger matrin-like protein antibody; Zinc finger protein 638 antibody; ZN638_HUMAN antibody; ZNF 638 antibody; Znf638 antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Synthesized peptide derived from the Internal region of Human NP220.
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
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抗体亚型:IgG
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纯化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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产品提供形式:Liquid
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应用范围:WB, IHC, ELISA
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推荐稀释比:
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Transcription factor that binds to cytidine clusters in double-stranded DNA. Plays a key role in the silencing of unintegrated retroviral DNA: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed. Mediates transcriptional repression of unintegrated viral DNA by specifically binding to the cytidine clusters of retroviral DNA and mediating the recruitment of chromatin silencers, such as the HUSH complex, SETDB1 and the histone deacetylases HDAC1 and HDAC4. Acts as an early regulator of adipogenesis by acting as a transcription cofactor of CEBPs (CEBPA, CEBPD and/or CEBPG), controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1. May also regulate alternative splicing of target genes during adipogenesis.
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基因功能参考文献:
- ZNF638 is a novel and early regulator of adipogenesis that works as a transcription cofactor of C/EBPs. PMID: 21602272
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亚细胞定位:Nucleus speckle.
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数据库链接:
HGNC: 17894
OMIM: 614349
KEGG: hsa:27332
STRING: 9606.ENSP00000264447
UniGene: Hs.434401
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