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  4. ZNF346 Antibody

ZNF346 Antibody

  • 货号：
    CSB-PA026691ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA026691ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA026691ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA026691ESR1HU at dilution of 1:100
    • Immunoprecipitating ZNF346 in HepG2 whole cell lysate
      Lane 1: Rabbit control IgG (1µg) instead of CSB-PA026691ESR1HU in HepG2 whole cell lysate. For western blotting, a HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG was used as the secondary antibody (1/50000)
      Lane 2: CSB-PA026691ESR1HU (4µg) + HepG2 whole cell lysate (500µg)
      Lane 3: HepG2 whole cell lysate (20µg)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ZNF346 Polyclonal antibody
  • Uniprot No.：
    Q9UL40
  • 基因名：
    ZNF346
  • 别名：
    DKFZp547M223 antibody; Double stranded RNA binding zinc finger protein antibody; Double stranded RNA binding zinc finger protein JAZ antibody; JAZ antibody; Just another zinc finger protein antibody; Zfp346 antibody; Zinc finger protein 346 antibody; ZN346_HUMAN antibody; Znf346 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Zinc finger protein 346 protein (1-294AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IP
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IP 1:200-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity. May bind to specific miRNA hairpins.
  • 基因功能参考文献：
    1. JAZ directly binds E2F1 in vitro in a dsRNA-independent manner, and JAZ's dsRNA binding ZF domains, which are necessary for localizing JAZ to the nucleus, are required for repression of transcriptional activity in vivo. PMID: 21715977
    2. JAZ is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism PMID: 15254228
  • 亚细胞定位：
    Nucleus, nucleolus. Cytoplasm. Note=Nuclear at steady state, primarily in the nucleolus. Shuttles between the nucleus and cytoplasm when associated with XPO5.
  • 数据库链接：

    HGNC: 16403

    OMIM: 605308

    KEGG: hsa:23567

    STRING: 9606.ENSP00000350869

    UniGene: Hs.484259