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ZNF300 Antibody

  • 货号：
    CSB-PA026653LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ZNF300 Polyclonal antibody
  • Uniprot No.：
    Q96RE9
  • 基因名：
    ZNF300
  • 别名：
    DKFZp686B24204 antibody; Kruppel like zinc finger protein antibody; OTTHUMP00000160554 antibody; OTTHUMP00000206798 antibody; Zinc finger protein 300 antibody; ZN300_HUMAN antibody; ZNF300 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Zinc finger protein 300 protein (1-300AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ZNF300 Antibody (CSB-PA026653LA01HU)，的标记方式是Non-conjugated。对于ZNF300 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA026653LB01HU ZNF300 Antibody, HRP conjugated ELISA
    FITC CSB-PA026653LC01HU ZNF300 Antibody, FITC conjugated
    Biotin CSB-PA026653LD01HU ZNF300 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has a transcriptional repressor activity.
  • 基因功能参考文献：
    1. Our findings further support ZNF300P1 as frequently methylated in ovarian cancer and reveal a novel function for ZNF300P1 lincRNA expression PMID: 24393131
    2. A novel function for ZNF300 in tumour development was identified that may uniquely link inflammation and NF-kappa B to tumourigenesis in humans but not in mice. PMID: 21777376
    3. Data show that co-expression of ZNF300 and Egr1 lead to enhanced IL-2Rbeta promoter activity, and suggest that ZNF300 is another regulator of the human IL-2Rbeta promoter. PMID: 20585888
    4. ZNF300 was activated by PU.1 and suggested that the regulation may be involved in the progression of leukemia development and hematopoietic differentiation. PMID: 20471086
    5. ZNF-300 and novel splice variant ZNF300-B are both expressed highly in human testis. PMID: 17541838
    6. Results show that the ZNF300 gene encodes a 68-kDa nuclear protein that binds DNA in a sequence-specific manner. PMID: 18350257

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 组织特异性：
    Expressed mostly in heart, skeletal muscle and brain. Isoform 1 and isoform 2 are highly expressed in testis.
  • 数据库链接：

    HGNC: 13091

    OMIM: 612429

    KEGG: hsa:91975

    STRING: 9606.ENSP00000397178

    UniGene: Hs.134885