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ZFR Antibody

  • 货号：
    CSB-PA842700LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of HepG2 cells with CSB-PA842700LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ZFR Polyclonal antibody
  • Uniprot No.：
    Q96KR1
  • 基因名：
    ZFR
  • 别名：
    FLJ41312 antibody; hZFR antibody; M phase phosphoprotein homolog antibody; M-phase phosphoprotein homolog antibody; zfr antibody; ZFR_HUMAN antibody; zinc finger RNA binding protein antibody; Zinc finger RNA-binding protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Zinc finger RNA-binding protein (150-268AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ZFR Antibody (CSB-PA842700LA01HU)，的标记方式是Non-conjugated。对于ZFR Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA842700LB01HU ZFR Antibody, HRP conjugated ELISA
    FITC CSB-PA842700LC01HU ZFR Antibody, FITC conjugated
    Biotin CSB-PA842700LD01HU ZFR Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic shuttling of STAU2. Binds to DNA and RNA.
  • 基因功能参考文献：
    1. ZFR expression is tightly controlled during macrophage development; monocytes express truncated ZFR isoforms, while macrophages induce full-length ZFR to modulate macrophage-specific alternative splicing. PMID: 29559679
    2. Identified a new circRNA, circZFR, that was significantly upregulated in papillary thyroid carcinoma (PTC). CircZFR could promote C8orf4 expression via serving as a competing endogenous RNA of miR-1261 in PTC cells. Rescue assays indicated that restoration of C8orf4 significantly attenuated the inhibitory effects of circZFR knockdown on PTC cell proliferation, migration and invasion. PMID: 29842886
    3. polyadenylation allows differential negative feedback of human miRNA miR-579 on its host gene ZFR PMID: 25799583
  • 亚细胞定位：
    Nucleus. Cytoplasm. Cytoplasmic granule. Chromosome.
  • 组织特异性：
    Expressed in lung, liver, lymphocytes, heart, pancreas, placenta, brain and kidney.
  • 数据库链接：

    HGNC: 17277

    OMIM: 615635

    KEGG: hsa:51663

    STRING: 9606.ENSP00000265069

    UniGene: Hs.435231