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ZDHHC15 Antibody

  • 货号:
    CSB-PA842720LA01HU
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • Immunofluorescent analysis of HepG2 cells using CSB-PA842720LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA842720LA01HU at dilution of 1:100
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) ZDHHC15 Polyclonal antibody
  • Uniprot No.:
    Q96MV8
  • 基因名:
    ZDHHC15
  • 别名:
    ZDHHC15; UNQ1969/PRO4501; Palmitoyltransferase ZDHHC15; Acyltransferase ZDHHC15; Zinc finger DHHC domain-containing protein 15; DHHC-15
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human Palmitoyltransferase ZDHHC15 protein (239-337AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated

    本页面中的产品,ZDHHC15 Antibody (CSB-PA842720LA01HU),的标记方式是Non-conjugated。对于ZDHHC15 Antibody,我们还提供其他标记。见下表:

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA842720LB01HU ZDHHC15 Antibody, HRP conjugated ELISA
    FITC CSB-PA842720LC01HU ZDHHC15 Antibody, FITC conjugated
    Biotin CSB-PA842720LD01HU ZDHHC15 Antibody, Biotin conjugated ELISA
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, IHC, IF
  • 推荐稀释比:
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates. Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA. Palmitoylates IGF2R and SORT1, promoting their partitioning to an endosomal membrane subdomain where they can interact with the retromer cargo-selective complex. Thereby, regulates retrograde transport from endosomes to the Golgi apparatus of these lysosomal sorting receptors and plays a role in trafficking of lysosomal proteins. In the nervous system, catalyzes the palmitoylation of DLG4/PSD95 and regulates its synaptic clustering and function in synaptogenesis. Could be involved in the differentiation of dopaminergic neurons and the development of the diencephalon. Could also catalyze the palmitoylation of GAP43. Could also palmitoylate DNAJC5 and regulate its localization to the Golgi membrane. Could also palmitoylate FYN as shown in vitro.
  • 相关疾病:
    Mental retardation, X-linked 91 (MRX91)
  • 亚细胞定位:
    Golgi apparatus membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic density.
  • 蛋白家族:
    DHHC palmitoyltransferase family
  • 组织特异性:
    Expressed in placenta, liver, lung, kidney, heart and brain.
  • 数据库链接:

    HGNC: 20342

    OMIM: 300576

    KEGG: hsa:158866

    STRING: 9606.ENSP00000362465

    UniGene: Hs.253211