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ZC4H2 Antibody

  • 货号：
    CSB-PA873628LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Mouse spleen tissue
      All lanes: ZC4H2 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 27, 16, 24, 21, 26 kDa
      Observed band size: 27 kDa
    • Immunofluorescent analysis of Hela cells using CSB-PA873628LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ZC4H2 Polyclonal antibody
  • Uniprot No.：
    Q9NQZ6
  • 基因名：
    ZC4H2
  • 别名：
    HCA127 antibody; Hepatocellular carcinoma-associated antigen 127 antibody; KIAA1166 antibody; OTTHUMP00000023432 antibody; Zc4h2 antibody; ZC4H2_HUMAN antibody; Zinc finger C4H2 domain containing antibody; Zinc finger C4H2 domain-containing protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Zinc finger C4H2 domain-containing protein (1-224AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ZC4H2 Antibody (CSB-PA873628LA01HU)，的标记方式是Non-conjugated。对于ZC4H2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA873628LB01HU ZC4H2 Antibody, HRP conjugated ELISA
    FITC CSB-PA873628LC01HU ZC4H2 Antibody, FITC conjugated
    Biotin CSB-PA873628LD01HU ZC4H2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in interneurons differentiation. Involved in neuronal development and in neuromuscular junction formation.
  • 基因功能参考文献：
    1. The present patient confirms that female carriers can also be severely affected. Systematic clinical investigations of both males and females are needed to define the variety in nature and severity of phenotypes related to ZC4H2 variants. PMID: 28345801
    2. ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons PMID: 26056227
    3. ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity. PMID: 23623388
  • 相关疾病：
    Wieacker-Wolf syndrome (WRWF)
  • 亚细胞定位：
    Cytoplasm. Nucleus. Cell junction, synapse, postsynaptic cell membrane. Note=Upon transfection into mouse primary hippocampal neurons, localizes at excitatory, but not inhibitory, postsynaptic sites.
  • 组织特异性：
    Expressed in fetal tissues, including in brain, intestine, lung, kidney and muscle. Isoform 1 is expressed in numerous fetal brain regions. Isoform 3 is highly expressed in numerous fetal brain regions and spinal cord.
  • 数据库链接：

    HGNC: 24931

    OMIM: 300897

    KEGG: hsa:55906

    STRING: 9606.ENSP00000363972

    UniGene: Hs.28249