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ZC3H13 Antibody

  • 货号：
    CSB-PA004565
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of A549 cells using ZC3H13 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q5T200
  • 基因名：
    ZC3H13
  • 别名：
    2600010B19Rik antibody; 3110050K21Rik antibody; 4930570G11Rik antibody; C87618 antibody; DKFZp434D1812 antibody; FLJ35669 antibody; KIAA0853 antibody; ZC3H13 antibody; ZC3HD_HUMAN antibody; Zinc finger CCCH domain-containing protein 13 antibody; zinc finger CCCH type containing 13 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human ZC3H13.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs at the 3'-UTR. Controls embryonic stem cells (ESCs) pluripotency via its role in m6A methylation. In the WMM complex, anchors component of the MACOM subcomplex in the nucleus. Also required for bridging WTAP to the RNA-binding component RBM15 (RBM15 or RBM15B).
  • 基因功能参考文献：
    1. This study identified ZC3H13 significantly associated loci with a biologically plausible role in schizophrenia. PMID: 24507884
  • 亚细胞定位：
    Nucleus speckle. Nucleus, nucleoplasm.
  • 数据库链接：

    HGNC: 20368

    OMIM: 616453

    KEGG: hsa:23091

    STRING: 9606.ENSP00000282007

    UniGene: Hs.136102