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YPEL3 Antibody

  • 货号：
    CSB-PA026272LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA026272LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) YPEL3 Polyclonal antibody
  • Uniprot No.：
    P61236
  • 基因名：
    YPEL3
  • 别名：
    Protein yippee-like 3 antibody; Small ubiquitinated apoptotic protein antibody; Yippee like 3 antibody; Yippee-like 3 (Drosophila) antibody; Ypel3 antibody; YPEL3_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protein yippee-like 3 protein (1-119AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，YPEL3 Antibody (CSB-PA026272LA01HU)，的标记方式是Non-conjugated。对于YPEL3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA026272LB01HU YPEL3 Antibody, HRP conjugated ELISA
    FITC CSB-PA026272LC01HU YPEL3 Antibody, FITC conjugated
    Biotin CSB-PA026272LD01HU YPEL3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in proliferation and apoptosis in myeloid precursor cells.
  • 基因功能参考文献：
    1. Expression of the YPEL3 gene was upregulated in human colonic adenocarcinoma tissue. PMID: 29988027
    2. Data show that YPEL3 is downregulated in nasopharyngeal carcinoma (NPC) cell lines and tissue samples and it suppresses NPC EMT and metastasis by suppressing the Wnt/beta-catenin signaling pathway. PMID: 27400785
    3. YPEL3 expression, which is induced by the removal of estrogen or treatment with tamoxifen triggers cellular senescence in MCF-7 cells while loss of YPEL3 increases the growth rate of MCF-7 cells. PMID: 21671470
    4. YPEL3 is downregulated in colon tumors. PMID: 21267786
    5. In this review we show that transcriptionally active forms of p73 and p63, family members of p53, can transactivate the human YPEL3 gene[review] PMID: 21196260
    6. Findings point to YPEL3 being a novel tumor suppressor, which upon induction triggers a permanent growth arrest in human tumor and normal cells. PMID: 20388804

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  • 亚细胞定位：
    Nucleus, nucleolus.
  • 蛋白家族：
    Yippee family
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 18327

    OMIM: 609724

    KEGG: hsa:83719

    STRING: 9606.ENSP00000381821

    UniGene: Hs.513491