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YIPF3 Antibody

  • 货号：
    CSB-PA863928LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Mouse heart tissue, Mouse liver tissue, Mouse brain tissue, Mouse stomach tissue
      All lanes: YIPF3 antibody at 3μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 39 kDa
      Observed band size: 39 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA863928LA01HU at dilution of 1:100
    • Immunofluorescent analysis of PC-3 cells using CSB-PA863928LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) YIPF3 Polyclonal antibody
  • Uniprot No.：
    Q9GZM5
  • 基因名：
    YIPF3
  • 别名：
    YIPF3; C6orf109; KLIP1; Protein YIPF3; Killer lineage protein 1; Natural killer cell-specific antigen KLIP1; YIP1 family member 3
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Protein YIPF3 protein (2-148AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，YIPF3 Antibody (CSB-PA863928LA01HU)，的标记方式是Non-conjugated。对于YIPF3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA863928LB01HU YIPF3 Antibody, HRP conjugated ELISA
    FITC CSB-PA863928LC01HU YIPF3 Antibody, FITC conjugated
    Biotin CSB-PA863928LD01HU YIPF3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
  • 基因功能参考文献：
    1. The significance of YIPF3 protein for the maintenance of the morphology of the Golgi was tested by RNA interference, revealing a number of specific morphological changes to this organelle on their depletion. PMID: 27999994
    2. Knockdown of YIPF1 and YIPF2, but not that of YIPF6, also reduced intracellular glycans in HT-29 cells. Thus, we confirmed that YIPF1, YIPF2, and YIPF6 play a significant role in supporting normal glycan synthesis PMID: 28286305
    3. YIPF3 is synthesized in the ER as a N-glycosylated form (40 kDa), is then O-glycosylated in the Golgi apparatus to become a lower mobility form (46 kDa) and finally becomes a higher mobility form cleaved at its C-terminal luminal domain (36 kDa). PMID: 21757827
    4. identification and characterization of KLIP-1, a novel transmembrane protein whose expression correlates with hematopoietic activity PMID: 12490290
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein. Cytoplasm. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Note=Localization to the cytoplasm or to the cell membrane is developmentally and ontogenetically regulated.
  • 蛋白家族：
    YIP1 family
  • 组织特异性：
    Expressed by nucleated hematopoietic cells (at protein level).
  • 数据库链接：

    HGNC: 21023

    OMIM: 609775

    KEGG: hsa:25844

    STRING: 9606.ENSP00000361499

    UniGene: Hs.440950