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YEATS2 Antibody

  • 货号：
    CSB-PA004540
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of 293 cells using YEATS2 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9ULM3
  • 基因名：
    YEATS2
  • 别名：
    FLJ10201 antibody; FLJ12841 antibody; FLJ13308 antibody; FLJ33401 antibody; FLJ34335 antibody; KIAA1197 antibody; YEATS domain containing 2 antibody; YEATS domain-containing protein 2 antibody; Yeats2 antibody; YETS2_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human YEATS2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors.
  • 基因功能参考文献：
    1. YEATS2 is a selective histone crotonylation reader. PMID: 27103431
    2. YEATS2 gene is highly amplified in human non-small cell lung cancer (NSCLC) and is required for cancer cell growth and survival PMID: 29057918
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 25489

    OMIM: 613373

    KEGG: hsa:55689

    STRING: 9606.ENSP00000306983

    UniGene: Hs.632575