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XPR1 Antibody

  • 货号：
    CSB-PA026228GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9UBH6
  • 基因名：
    XPR1
  • 别名：
    FLJ90308 antibody; OTTHUMP00000033084 antibody; OTTHUMP00000033085 antibody; Polytropic murine leukamia virus receptor SYG 1 antibody; Polytropic murine leukamia virus receptor SYG1 antibody; Protein SYG1 homolog antibody; SYG 1 antibody; SYG1 antibody; SYG1 protein antibody; X-receptor antibody; X3 antibody; Xenotropic and polytropic murine leukemia virus receptor X3 antibody; Xenotropic and polytropic retrovirus receptor antibody; Xenotropic and polytropic retrovirus receptor 1 antibody; XPR 1 antibody; XPR1 antibody; XPR1 protein antibody; XPR1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human XPR1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in phosphate homeostasis. Mediates phosphate export from the cell. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules.
  • 基因功能参考文献：
    1. These results confirm that loss of XPR1-mediated phosphate export function causes primary familial brain calcification, occurring in less than 8 % of cases negative for the other genes, and may be responsible for parkinsonism. PMID: 27230854
    2. XPR1 mutations alter phosphate export and phosphate homeostasis in primary familial brain calcification. PMID: 25938945
    3. These studies suggest that the expression of Xpr1 and certain genotypes of the RNASEL gene, which could restrict XMRV infection, may play important roles in defining XMRV tropisms in certain cell types. PMID: 20410264
  • 相关疾病：
    Basal ganglia calcification, idiopathic, 6 (IBGC6)
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    SYG1 (TC 2.A.94) family
  • 组织特异性：
    Widely expressed. Detected in spleen, lymph node, thymus, leukocytes, bone marrow, heart, kidney, pancreas and skeletal muscle.
  • 数据库链接：

    HGNC: 12827

    OMIM: 605237

    KEGG: hsa:9213

    STRING: 9606.ENSP00000356562

    UniGene: Hs.227656