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XPNPEP1 Antibody

  • 货号：
    CSB-PA878859HA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: Xaa-Pro aminopeptidase 1 antibody at 8μg/ml
      Lane 1: Mouse small intestine tissue
      Lane 2: Mouse stomach tissue
      Lane 3: Mouse kidney tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 70, 68, 75, 73 kDa
      Observed band size: 70 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA878859HA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) XPNPEP1 Polyclonal antibody
  • Uniprot No.：
    Q9NQW7
  • 基因名：
    XPNPEP1
  • 别名：
    Aminoacylproline aminopeptidase antibody; aminopeptidase P, cytosolic antibody; APP1 antibody; Cytosolic aminopeptidase P antibody; RP11 451M19.1 antibody; sAmp antibody; Soluble aminopeptidase P antibody; soluble antibody; X Pro aminopeptidase 1 antibody; X prolyl aminopeptidase (aminopeptidase P) 1 antibody; X prolyl aminopeptidase (Aminopeptidase P) 1 soluble antibody; X prolyl aminopeptidase 1 antibody; X prolyl aminopeptidase 1 soluble antibody; X-Pro aminopeptidase 1 antibody; X-prolyl aminopeptidase 1 antibody; Xaa Pro aminopeptidase 1 antibody; Xaa-Pro aminopeptidase 1 antibody; XPNPEP 1 antibody; XPNPEP antibody; xpnpep1 antibody; XPNPEPL antibody; XPNPEPL1 antibody; XPP1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Xaa-Pro aminopeptidase 1 protein (2-623AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，XPNPEP1 Antibody (CSB-PA878859HA01HU)，的标记方式是Non-conjugated。对于XPNPEP1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA878859HB01HU XPNPEP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA878859HC01HU XPNPEP1 Antibody, FITC conjugated
    Biotin CSB-PA878859HD01HU XPNPEP1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro.
  • 基因功能参考文献：
    1. Alanine replacement of Arg535 destabilizes the AMPP dimer and guanidine hydrochloride restores the native monomer-dimer equilibrium. It is proposed that Arg535 plays an important role in AMMP catalysis and in stabilization of the catalytically active dimeric state PMID: 29351301
    2. These data suggest that progesterone-induced increases in AP-P may contribute to the development of oral contraceptive pill-induced hypertension in susceptible Women. PMID: 19126663
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Peptidase M24B family
  • 组织特异性：
    Expressed in all tissues tested, including pancreas, heart, muscle, kidney, liver, lung and brain. Highest levels in pancreas.
  • 数据库链接：

    HGNC: 12822

    OMIM: 602443

    KEGG: hsa:7511

    STRING: 9606.ENSP00000421566

    UniGene: Hs.390623