Your Good Partner in Biology Research

WDR41 Antibody

  • 中文名称:
    WDR41兔多克隆抗体
  • 货号:
    CSB-PA864011LA01HU
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • Immunofluorescence staining of U251 cells with CSB-PA864011LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) WDR41 Polyclonal antibody
  • Uniprot No.:
    Q9HAD4
  • 基因名:
    WDR41
  • 别名:
    FLJ10904 antibody; MSTP048 antibody; WD repeat domain 41 antibody; WD repeat protein 41 antibody; WD repeat-containing protein 41 antibody; WDR 41 antibody; WDR41 antibody; WDR41_HUMAN antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human WD repeat-containing protein 41 protein (7-284AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated

    本页面中的产品,WDR41 Antibody (CSB-PA864011LA01HU),的标记方式是Non-conjugated。对于WDR41 Antibody,我们还提供其他标记。见下表:

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA864011LB01HU WDR41 Antibody, HRP conjugated ELISA
    FITC CSB-PA864011LC01HU WDR41 Antibody, FITC conjugated
    Biotin CSB-PA864011LD01HU WDR41 Antibody, Biotin conjugated ELISA
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, IF
  • 推荐稀释比:
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity.
  • 基因功能参考文献:
    1. Study describes the identification of two binding partners for C9orf72: SMCR8 and WDR41 and demonstrated that C9orf72/SMCR8/WDR41 interacts with the FIP200/Ulk1/ATG13/ATG101 complex. PMID: 27193190
    2. The peak of association was found in and around two genes, WDR41 and PDE8B, involved in dopamine signaling and development. PMID: 21502949
  • 亚细胞定位:
    Cytoplasm.
  • 数据库链接:

    HGNC: 25601

    OMIM: 617502

    KEGG: hsa:55255

    STRING: 9606.ENSP00000296679

    UniGene: Hs.482573