Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. WDPCP Antibody

WDPCP Antibody

  • 货号：
    CSB-PA528516LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA528516LA01HU at dilution of 1:100
    • Immunofluorescence staining of MCF-7 cells with CSB-PA528516LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) WDPCP Polyclonal antibody
  • Uniprot No.：
    O95876
  • 基因名：
    WDPCP
  • 别名：
    Bardet-Biedl syndrome 15 protein antibody; Chromosome 2 open reading frame 86 antibody; DKFZp686C12204 antibody; Fritz antibody; FRITZ_HUMAN antibody; hFrtz antibody; WD repeat containing protein C2orf86 antibody; WD repeat-containing and planar cell polarity effector protein antibody; WD repeat-containing and planar cell polarity effector protein fritz homolog antibody; WDPCP antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human WD repeat-containing and planar cell polarity effector protein fritz homolog protein (621-737AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，WDPCP Antibody (CSB-PA528516LA01HU)，的标记方式是Non-conjugated。对于WDPCP Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA528516LB01HU WDPCP Antibody, HRP conjugated ELISA
    FITC CSB-PA528516LC01HU WDPCP Antibody, FITC conjugated
    Biotin CSB-PA528516LD01HU WDPCP Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies.
  • 基因功能参考文献：
    1. Inflammatory cytokines cause reduced WDPCP expression, which contributes to impaired ciliogenesis in human rhinosinusitis. PMID: 28001338
    2. study linked mutations in Fritz to Bardet-Biedl and Meckel-Gruber syndromes, a notable link given that other genes mutated in these syndromes also influence collective cell movement and ciliogenesis PMID: 20671153
  • 相关疾病：
    Bardet-Biedl syndrome 15 (BBS15); Congenital heart defects, hamartomas of tongue, and polysyndactyly (CHDTHP)
  • 亚细胞定位：
    Cell membrane. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    WD repeat fritz family
  • 数据库链接：

    HGNC: 28027

    OMIM: 217085

    KEGG: hsa:51057

    STRING: 9606.ENSP00000272321

    UniGene: Hs.414952