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VPS51 Antibody

  • 货号：
    CSB-PA883424LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, U251 whole cell lysate, A549 whole cell lysate, U87 whole cell lysate
      All lanes: VPS51 antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 87, 73 kDa
      Observed band size: 87 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) VPS51 Polyclonal antibody
  • Uniprot No.：
    Q9UID3
  • 基因名：
    VPS51
  • 别名：
    ANG2 antibody; ANG3 antibody; Another new gene 2 protein antibody; C11orf3 antibody; chromosome 11 open reading frame 2 antibody; Fat free homolog antibody; ffr antibody; FFR_HUMAN antibody; FFR|FLJ13879 antibody; FLJ36472 antibody; Protein fat-free homolog antibody; Vacuolar protein sorting 51 homolog antibody; VPS51 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Vacuolar protein sorting-associated protein 51 homolog protein (595-673AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，VPS51 Antibody (CSB-PA883424LA01HU)，的标记方式是Non-conjugated。对于VPS51 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA883424LB01HU VPS51 Antibody, HRP conjugated ELISA
    FITC CSB-PA883424LC01HU VPS51 Antibody, FITC conjugated
    Biotin CSB-PA883424LD01HU VPS51 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
  • 基因功能参考文献：
    1. A dityrosine motif of Ang2 interacts with a highly conserved groove in Syntaxin 6. PMID: 23932592
    2. Ang2 is the missing component of the Golgi-associated retrograde protein complex in most eukaryotes. PMID: 20685960
  • 亚细胞定位：
    Golgi apparatus, trans-Golgi network. Recycling endosome.
  • 蛋白家族：
    VPS51 family
  • 数据库链接：

    HGNC: 1172

    OMIM: 615738

    KEGG: hsa:738

    STRING: 9606.ENSP00000279281

    UniGene: Hs.277517