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  4. VPREB3 Antibody

VPREB3 Antibody

  • 货号：
    CSB-PA025888GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9UKI3
  • 基因名：
    VPREB3
  • 别名：
    N27C7 2 antibody; N27C7-2 antibody; Pre B lymphocyte protein 3 antibody; Pre-B lymphocyte protein 3 antibody; PRO619 antibody; Protein VPreB3 antibody; UNQ355 antibody; VPRE3_HUMAN antibody; VPREB3 antibody; VpreB3 protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human VPREB3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells.
  • 基因功能参考文献：
    1. A possible role for VPREB3 in aldosterone biosynthesis. PMID: 25861052
    2. levels of VPREB3 mRNA in aldosterone-producing adenomas directly correlate to plasma aldosterone concentrations in peripheral blood of respective patients PMID: 25861052
    3. mouse VpreB3 associates with mu heavy chains early in pre-B cell receptor biosynthesis PMID: 8491176
    4. VpreB3 may play a role in the regulation of the maturation and secretion of free IgLC in chicken B cells PMID: 14670953
    5. the combined immunohistochemical detection of VPREB3 and ID3 is applicable to the routine diagnostic in case of mature aggressive B-cell lymphomas. PMID: 24493312
    6. Data show that the absence of VpreB3 is virtually always associated with wild-type c-MYC alleles. PMID: 20823132
    7. the present study confirms the co-existence of surrogate lambda and kappa receptors that are proposed to work in concert to promote B lymphocyte maturation. PMID: 15757909

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  • 蛋白家族：
    Immunoglobulin superfamily
  • 组织特异性：
    Expressed in B-cell precursors. Expressed in fetal liver, bone marrow, spleen and lymph node.
  • 数据库链接：

    HGNC: 12710

    OMIM: 605017

    KEGG: hsa:29802

    STRING: 9606.ENSP00000248948

    UniGene: Hs.136713