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USP50 Antibody

  • 货号：
    CSB-PA791798
  • 规格：
    ￥2024
  • 图片：
    • Western blot analysis of extracts from A549 cells, using USP50 antiobdy.
    • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using USP50 antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) USP50 Polyclonal antibody
  • Uniprot No.：
    Q70EL3
  • 基因名：
    USP50
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from C-terminal of Human USP50.
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has no peptidase activity.
  • 基因功能参考文献：
    1. verexpression of USP50 has no effect on Ku70 mRNA levels, while it reduces Ku70 protein levels by promoting Ku70 degradation, suggesting that USP50 may indirectly regulate Ku70 protein stability. PMID: 29101126
    2. the deubiquitinating enzyme USP50 binds to the ASC protein and subsequently regulates the inflammasome signaling pathway. PMID: 28094437
    3. USP50 may act through a HSP90-dependent mechanism to counteract CDC25B mitotic inducing activity and prevent Wee1 degradation. PMID: 20930503
    4. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  • 蛋白家族：
    Peptidase C19 family
  • 组织特异性：
    Weakly expressed in a few tissues.
  • 数据库链接：

    HGNC: 20079

    KEGG: hsa:373509

    STRING: 9606.ENSP00000434676

    UniGene: Hs.677758