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USP34 Antibody

  • 货号：
    CSB-PA025725GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q70CQ2
  • 基因名：
    USP34
  • 别名：
    Deubiquitinating enzyme 34 antibody; FLJ43910 antibody; KIAA0570 antibody; KIAA0729 antibody; MGC104459 antibody; Ubiquitin carboxyl terminal hydrolase 34 antibody; Ubiquitin carboxyl-terminal hydrolase 34 antibody; Ubiquitin specific processing protease 34 antibody; Ubiquitin specific protease 34 antibody; Ubiquitin thioesterase 34 antibody; Ubiquitin thiolesterase 34 antibody; Ubiquitin-specific-processing protease 34 antibody; UBP34_HUMAN antibody; USP 34 antibody; Usp34 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Human USP34
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
  • 基因功能参考文献：
    1. the role of USP34 on epithelial-mesenchymal (EMT) induction and its effects on mammary epithelial stem cells, was investigated. PMID: 28499884
    2. CONCLUSIONS: USP34 gene polymorphisms (rs17008097 and rs17008940) may not be associated with Polycystic ovary syndrome in the Han Chinese women. PMID: 25975428
  • 蛋白家族：
    Peptidase C19 family
  • 组织特异性：
    Expressed in brain at low level.
  • 数据库链接：

    HGNC: 20066

    OMIM: 615295

    KEGG: hsa:9736

    STRING: 9606.ENSP00000381577

    UniGene: Hs.644708