USMG5 Antibody
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货号:CSB-PA836231LA01HU
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规格:¥440
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促销:
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图片:
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其他:
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) USMG5 Polyclonal antibody
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Uniprot No.:Q96IX5
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基因名:USMG5
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别名:bA792D24.4 antibody; DAPIT antibody; DKFZp566D211 antibody; HCV F-transactivated protein 2 antibody; HCVFTP2 antibody; MGC14697 antibody; Up regulated during skeletal muscle growth 5 homolog (mouse) antibody; Up-regulated during skeletal muscle growth protein 5 antibody; Usmg5 antibody; USMG5_HUMAN antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Up-regulated during skeletal muscle growth protein 5 protein (2-58AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
本页面中的产品,USMG5 Antibody (CSB-PA836231LA01HU),的标记方式是Non-conjugated。对于USMG5 Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA, IF
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推荐稀释比:
Application Recommended Dilution IF 1:50-1:200 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. ATP5MK is a minor subunit of the mitochondrial membrane ATP synthase required for dimerization of the ATP synthase complex and as such regulates ATP synthesis in the mitochondria.
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基因功能参考文献:
- DAPIT over-expression thus appears to modulate mitochondrial functions and alter cellular regulations, promote anaerobic metabolism and induce EMT-like transition. PMID: 26161955
- confirm the mitochondrial presence of DAPIT on cellular level. We also show that DAPIT is localized in lysosomes of HUVEC and HEK 293T cells PMID: 22688299
- a critical role of DAPIT in maintaining the ATP synthase population in mitochondria and raise an intriguing possibility of active role of DAPIT in cellular energy metabolism. PMID: 21345788
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亚细胞定位:Mitochondrion membrane; Single-pass membrane protein.
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数据库链接:
HGNC: 30889
OMIM: 615204
KEGG: hsa:84833
STRING: 9606.ENSP00000311245
UniGene: Hs.500921
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