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UBXN4 Antibody

  • 中文名称：
    UBXN4兔多克隆抗体
  • 货号：
    CSB-PA025536GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q92575
  • 基因名：
    UBXN4
  • 别名：
    UBXN4 antibody; KIAA0242 antibody; UBXD2 antibody; UBXDC1 antibody; UBX domain-containing protein 4 antibody; Erasin antibody; UBX domain-containing protein 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human UBXN4
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.
  • 基因功能参考文献：
    1. Erasin/UBXD2 may be involved in endoplasmic-reticulum-associated protein degradation and in Alzheimer's disease. PMID: 16968747
    2. Knockdown of erasin, a platform for p97/VCP and ubiquilin binding, or knockdown of ubiquilin in human cells slowed degradation of two classical endoplasmic reticulum-associated protein degradation substrates. PMID: 19822669
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus envelope.
  • 组织特异性：
    Expressed in many tissues, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Accumulates in Alzheimer disease-afflicted brains (at protein level).
  • 数据库链接：

    HGNC: 14860

    OMIM: 611216

    KEGG: hsa:23190

    STRING: 9606.ENSP00000272638

    UniGene: Hs.591242