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TULP3 Antibody

  • 货号：
    CSB-PA025348GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O75386
  • 基因名：
    TULP3
  • 别名：
    MGC45295 antibody; Tubby like protein 3 antibody; Tubby related protein 3 antibody; Tubby-like protein 3 antibody; Tubby-related protein 3 antibody; TUBL 3 antibody; TUBL3 antibody; TULP 3 antibody; TULP3 antibody; TULP3_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human TULP3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis. During adipogenesis, regulates ciliary trafficking of FFAR4 in preadipocytes.
  • 基因功能参考文献：
    1. Data demonstrated that pancreatic cancer patients exhibiting high transcriptional levels of TULP3 showed a poor overall survival rate. PMID: 24668219
  • 亚细胞定位：
    Nucleus. Cell membrane. Cell projection, cilium. Cytoplasm. Secreted.
  • 蛋白家族：
    TUB family
  • 组织特异性：
    Expressed at high levels in testis, ovaries, thyroid, and spinal chord.
  • 数据库链接：

    HGNC: 12425

    OMIM: 604730

    KEGG: hsa:7289

    STRING: 9606.ENSP00000380321

    UniGene: Hs.655333