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TUBB2A Antibody

  • 货号：
    CSB-PA025320LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: TUBB2A antibody at 14µg/ml
      Lane 1: MCF-7 whole cell lysate
      Lane 2: Hela whole cell lysate
      Lane 3: HepG2 whole cell lysate
      Lane 4: MDA-MB-231 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 50 kDa
      Observed band size: 50 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TUBB2A Polyclonal antibody
  • Uniprot No.：
    Q13885
  • 基因名：
  • 别名：
    TUBB2A antibody; TUBB2 antibody; Tubulin beta-2A chain antibody; Tubulin beta class IIa antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Tubulin beta-2A chain protein (1-445AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TUBB2A Antibody (CSB-PA025320LA01HU)，的标记方式是Non-conjugated。对于TUBB2A Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA025320LB01HU TUBB2A Antibody, HRP conjugated ELISA
    FITC CSB-PA025320LC01HU TUBB2A Antibody, FITC conjugated
    Biotin CSB-PA025320LD01HU TUBB2A Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
  • 基因功能参考文献：
    1. TUBB2A missense mutation is associated with arthrogryposis multiplex congenita, brain abnormalities, and severe developmental delay. PMID: 28840640
    2. study associates mutations in TUBB2A with the spectrum of "tubulinopathy" phenotypes PMID: 24702957
    3. This is the first study showing that paclitaxel neuropathy risk is influenced by polymorphisms regulating the expression of a beta-tubulin gene. PMID: 22718863
    4. Class II beta-tubulin may be very useful for immunohistochemical diagnosis of classical Hodgkin's lymphoma. PMID: 22449234
    5. Data suggest that the increased betaII- and betaIII-tubulin contributed significantly to the resistance phenotype. PMID: 22180309
    6. lack of mutations in early stage lung cancer PMID: 12209967
    7. Mutations of the beta-tubulin gene, which might be a contraindication for chemotherapy based on taxans, were very rare events in gastric cancer. PMID: 12861402

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  • 相关疾病：
    Cortical dysplasia, complex, with other brain malformations 5 (CDCBM5)
  • 亚细胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Tubulin family
  • 组织特异性：
    High expression in brain, where it represents 30% of all beta-tubulins.
  • 数据库链接：

    HGNC: 12412

    OMIM: 615101

    KEGG: hsa:7280

    STRING: 9606.ENSP00000369703

    UniGene: Hs.654543