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TUBA8 Antibody

  • 货号：
    CSB-PA025314GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9NY65
  • 基因名：
  • 别名：
    Alpha tubulin 8 antibody; Alpha-tubulin 8 antibody; TBA8_HUMAN antibody; Tuba8 antibody; TUBAL2 antibody; Tubulin alpha 8 chain antibody; Tubulin alpha chain like 2 antibody; Tubulin alpha chain-like 2 antibody; Tubulin alpha-8 chain antibody
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human TUBA8
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
  • 基因功能参考文献：
    1. Data provide evidence for a role of TUBA8 in hepatic fibrogenesis and malignancies making it a novel player in non-alcoholic steatohepatitis and hepatocellular carcinoma pathology. PMID: 28063004
    2. TUBA8 can play a role in the regulation of cell growth, proliferation, and cell migration in a cell-specific manner in vitro. PMID: 21872825
    3. TUBA8 is expressed at low levels in the developing human brain. PMID: 20466094
    4. Mutation of the variant alpha-tubulin TUBA8 results in polymicrogyria with optic nerve hypoplasia. PMID: 19896110
  • 相关疾病：
    Cortical dysplasia, complex, with other brain malformations 8 (CDCBM8)
  • 亚细胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Tubulin family
  • 组织特异性：
    Preferentially expressed in heart, skeletal muscle and testis. Expressed at low levels in the developing brain.
  • 数据库链接：

    HGNC: 12410

    OMIM: 605742

    KEGG: hsa:51807

    STRING: 9606.ENSP00000333326

    UniGene: Hs.137400