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TTLL7 Antibody

  • 货号：
    CSB-PA765082ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: TTLL7 antibody at 2.04µg/ml + Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 103, 78, 93 kDa
      Observed band size: 103 kDa
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA765082ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA765082ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TTLL7 Polyclonal antibody
  • Uniprot No.：
    Q6ZT98
  • 基因名：
    TTLL7
  • 别名：
    RP5-836J3.2 antibody; Testis development protein NYD-SP30 antibody; Ttll7 antibody; TTLL7_HUMAN antibody; Tubulin polyglutamylase TTLL7 antibody; Tubulin tyrosine ligase like family member 7 antibody; Tubulin--tyrosine ligase-like protein 7 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Tubulin polyglutamylase TTLL7 protein (1-260AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Polyglutamylase which modifies tubulin, generating polyglutamate side chains of variable lengths on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin. Mediates both ATP-dependent initiation and elongation steps of the polyglutamylation reaction. Preferentially modifies the beta-tubulin tail over an alpha-tail. Competes with monoglycylase TTLL3 for modification site on beta-tubulin substrate, thereby creating an anticorrelation between glycylation and glutamylation reactions. Required for neurite growth; responsible for the strong increase in tubulin polyglutamylation during postnatal neuronal maturation.
  • 亚细胞定位：
    Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, dendrite. Perikaryon.
  • 蛋白家族：
    Tubulin--tyrosine ligase family
  • 组织特异性：
    Highly expressed in the nervous system including spinal cord, thalamus, hippocampus, hypothalamus and cerebellum.
  • 数据库链接：

    HGNC: 26242

    KEGG: hsa:79739

    STRING: 9606.ENSP00000260505

    UniGene: Hs.445826