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TTC5 Antibody

  • 货号：
    CSB-PA822676LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: TTC5 antibody at 6µg/ml
      Lane 1: HepG2 whole cell lysate
      Lane 2: A549 whole cell lysate
      Lane 3: MCF-7 whole cell lysate
      Lane 4: Mouse kidney tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 49 kDa
      Observed band size: 49 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TTC5 Polyclonal antibody
  • Uniprot No.：
    Q8N0Z6
  • 基因名：
    TTC5
  • 别名：
    TTC5Tetratricopeptide repeat protein 5 antibody; TPR repeat protein 5 antibody; Stress-responsive activator of p300 antibody; Strap antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Tetratricopeptide repeat protein 5 protein (201-440AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TTC5 Antibody (CSB-PA822676LA01HU)，的标记方式是Non-conjugated。对于TTC5 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA822676LB01HU TTC5 Antibody, HRP conjugated ELISA
    FITC CSB-PA822676LC01HU TTC5 Antibody, FITC conjugated
    Biotin CSB-PA822676LD01HU TTC5 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2.
  • 基因功能参考文献：
    1. Human TTC5, a novel tetratricopeptide repeat domain containing gene, activates p53 and inhibits AP-1 pathway. PMID: 24091941
    2. TTC5 and EP300 cooperate to prevent excessive accumulation of MYC in AML cells and their sensitization to cell death. PMID: 23559008
    3. TTC5 is a novel cofactor regulating GR function in a stress-dependent manner. PMID: 21147850
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 数据库链接：

    HGNC: 19274

    KEGG: hsa:91875

    STRING: 9606.ENSP00000258821

    UniGene: Hs.98553