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TSTA3 Antibody

  • 货号：
    CSB-PA025200GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q13630
  • 基因名：
    TSTA3
  • 别名：
    3 5 epimerase/4 reductase antibody; 5-epimerase-4-reductase antibody; anti TSTA3 antibody; EC 1.1.1.271 antibody; FCL_HUMAN antibody; FX antibody; GDP 4 keto 6 deoxy D mannose 3 5 epimerase 4 reductase antibody; GDP 4 keto 6 deoxy D mannose epimerase reductase antibody; GDP L fucose synthase antibody; GDP-4-keto-6-deoxy-D-mannose-3 antibody; GDP-L-fucose synthase antibody; P35B antibody; Protein FX antibody; Red cell NADP(H) binding protein antibody; Red cell NADP(H)-binding protein antibody; SDR4E1 antibody; Short chain dehydrogenase/reductase family 4E member 1 antibody; Short-chain dehydrogenase/reductase family 4E member 1 antibody; Tissue specific transplantation antigen 3 antibody; Tissue specific transplantation antigen P35B antibody; TSTA3 antibody; TSTA3 antibody antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human TSTA3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
  • 基因功能参考文献：
    1. tissue-specific transplantation antigen P35B may serve as a novel biomarker for prognosis of patients with esophageal squamous cell carcinoma. PMID: 29950151
    2. The findings suggest that miR-125a-5p/miR-125b suppress the expression of TSTA3, which controls cell proliferation and invasion by regulating CXCR4 expression. In conclusion, a high expression of TSTA3 exerts a proto-oncogenic effect during carcinogenesis and serves as an independent molecular marker for breast cancerpatients. PMID: 26531722
    3. Data indicate that the structure of GDP-l-fucose synthase (FX) reveals the key catalytic residues. PMID: 23774504
    4. Tissue-specific transplantation antigen P35B (TSTA3) immune response-mediated metabolism coupling cell cycle to postreplication repair network in no-tumor hepatitis/cirrhotic tissues (HBV or HCV PMID: 22528125
  • 蛋白家族：
    NAD(P)-dependent epimerase/dehydratase family, Fucose synthase subfamily
  • 数据库链接：

    HGNC: 12390

    OMIM: 137020

    KEGG: hsa:7264

    STRING: 9606.ENSP00000398803

    UniGene: Hs.404119