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TSSK4 Antibody

  • 货号：
    CSB-PA877181
  • 规格：
    ￥2024
  • 图片：
    • Western blot analysis of extracts from HT-29 cells, using TSSK4 antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TSSK4 Polyclonal antibody
  • Uniprot No.：
    Q6SA08
  • 基因名：
    TSSK4
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human TSSK4.
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Serine/threonine kinase which is involved in male germ cell development and in mature sperm function. May be involved in the Cre/Creb signaling pathway. Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells. Phosphorylates CREM on 'Ser-116' in vitro. Phosphorylates ODF2 on 'Ser-95'.
  • 基因功能参考文献：
    1. TSSK4 was able to induce cell apoptosis in vitro depending on its kinase activity, which leads to abnormal testes weight and apoptosis, shedding light on its function in the process of spermatogenesis and/or spermiogenesis PMID: 25877358
    2. Observational study of gene-disease association. (HuGE Navigator) PMID: 20378615
    3. association of some single nucleotide polymorphisms in TSSK4 with male infertility. PMID: 18390560
    4. Observational study of gene-disease association. (HuGE Navigator) PMID: 18390560
  • 亚细胞定位：
    Cytoplasmic vesicle, secretory vesicle, acrosome. Cell projection, cilium, flagellum.
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family
  • 组织特异性：
    Expressed only in the testis.
  • 数据库链接：

    HGNC: 19825

    OMIM: 610711

    KEGG: hsa:283629

    STRING: 9606.ENSP00000339179

    UniGene: Hs.314432