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TSPAN7 Antibody

  • 货号：
    CSB-PA025165GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P41732
  • 基因名：
    TSPAN7
  • 别名：
    A15 antibody; CCG B7 antibody; CD231 antibody; CD231 antigen antibody; Cell surface glycoprotein A15 antibody; DXS1692E antibody; Membrane component chromosome X surface marker 1 antibody; Membrane component X chromosome surface marker 1 antibody; MRX58 antibody; MXS1 antibody; T cell acute lymphoblastic leukemia associated antigen 1 antibody; T-cell acute lymphoblastic leukemia-associated antigen 1 antibody; TALLA 1 antibody; TALLA antibody; TALLA-1 antibody; TALLA1 antibody; Tetraspanin 7 antibody; Tetraspanin-7 antibody; TM4SF2 antibody; TM4SF2b antibody; Transmembrane 4 superfamily 2b antibody; Transmembrane 4 superfamily member 2 antibody; Transmembrane protein A15 antibody; TSN7_HUMAN antibody; Tspan 7 antibody; Tspan-7 antibody; TSPAN7 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Human TSPAN7
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in cell proliferation and cell motility.
  • 基因功能参考文献：
    1. These results disclosed a previously uncharacterized role of TSPAN7 in the regulation of the expression and functional activity of DRD2 by postendocytic trafficking. PMID: 28223337
    2. The role of TSPAN7 in immune system response to HIV-1 is reviewed. TSPAN7 appears to be a positive regulator of actin nucleation and stabilization, through the ARP2/3 complex. By doing so, TSPAN7 limits HIV-1 endocytosis and maintains viral particles on actin-rich dendrites for an efficient transfer toward T lymphocytes. PMID: 28620031
    3. Elevated TSPAN7 may be associated with better outcomes for multiple myeloma patients. PMID: 25637218
    4. Loss of TSPAN7 is associated with metastasis in clear-cell renal cell carcinoma. PMID: 22213152
    5. This study identified that TSPAN7 as a key molecule for the functional maturation of dendritic spines via PICK1 and ampa receptor trafficking. PMID: 22445342
    6. TM4SF2 was identified as a putative antigenic target in Wegener's granulomatosis PMID: 20951001
    7. Studies indicate that The thymus leukemia (TL) antigen and CD8alphaalpha are interacting surface molecules that are expressed at the frontline of the mucosal immune system. PMID: 20850477
    8. The interaction of VP26 with tetraspanin-7 plays an essential role in normal HSV-1 replication. PMID: 20630051
    9. associated with spermatozoa PMID: 19535787
    10. The role of TMSF2 in mental retardation PMID: 14735593
    11. coding mutations in TSPAN7 are not associated with our cohort of autism patients PMID: 19339915

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  • 相关疾病：
    Mental retardation, X-linked 58 (MRX58)
  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Tetraspanin (TM4SF) family
  • 组织特异性：
    Not solely expressed in T-cells. Expressed in acute myelocytic leukemia cells of some patients.
  • 数据库链接：

    HGNC: 11854

    OMIM: 300096

    KEGG: hsa:7102

    STRING: 9606.ENSP00000367743

    UniGene: Hs.441664