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TRNAU1AP Antibody

  • 货号：
    CSB-PA025008GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9NX07
  • 基因名：
    TRNAU1AP
  • 别名：
    1110007F05Rik antibody; AA387999 antibody; FLJ20503 antibody; PRO1902 antibody; RP4 669K10.4 antibody; SECp43 antibody; tRNA selenocysteine 1-associated protein 1 antibody; tRNA selenocysteine associated protein 1 antibody; tRNA selenocysteine-associated protein 1 antibody; Trnau1ap antibody; TRSPAP1 antibody; TSAP1_HUMAN antibody; WI1 2643G14.2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human TRNAU1AP,SECP43
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis.
  • 基因功能参考文献：
    1. Knockdown of Trnau1ap reduced cell migration and proliferation. Knockdown of Trnau1ap blocked the PI3K/Akt signaling pathway. PMID: 29758194
    2. Data confirm interactions among components of the early steps of the selenocysteine biosynthesis pathway (SEPSECS, SECP43, SEPHS1, and SEPHS2); SECP43, which interacts with SEPSECS and SEPHS1, is a globular protein that forms oligomers in vivo. PMID: 28414460
    3. our studies delineating the multiple, coordinated protein-nucleic acid interactions between SECp43 and the selenoprotein cotranslational factors. PMID: 16508009
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    RRM TRSPAP family
  • 数据库链接：

    HGNC: 30813

    KEGG: hsa:54952

    STRING: 9606.ENSP00000362936

    UniGene: Hs.533626