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TRIM38 Antibody

  • 货号：
    CSB-PA024475LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: TRIM38 antibody at 4µg/ml + Jurkat whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 54 kDa
      Observed band size: 54 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TRIM38 Polyclonal antibody
  • Uniprot No.：
    O00635
  • 基因名：
    TRIM38
  • 别名：
    TRIM38 antibody; RNF15 antibody; RORET antibody; E3 ubiquitin-protein ligase TRIM38 antibody; EC 2.3.2.27 antibody; RING finger protein 15 antibody; RING-type E3 ubiquitin transferase TRIM38 antibody; Tripartite motif-containing protein 38 antibody; Zinc finger protein RoRet antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human E3 ubiquitin-protein ligase TRIM38 protein (45-259AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TRIM38 Antibody (CSB-PA024475LA01HU)，的标记方式是Non-conjugated。对于TRIM38 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA024475LB01HU TRIM38 Antibody, HRP conjugated ELISA
    FITC CSB-PA024475LC01HU TRIM38 Antibody, FITC conjugated
    Biotin CSB-PA024475LD01HU TRIM38 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    E3 ubiquitin-protein ligase. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling.
  • 基因功能参考文献：
    1. Data suggest that mRNA/protein levels of NLRP6 are down-regulated in synovial tissues and synoviocytes of rheumatoid arthritis (RA) patients compared to osteoarthritis patients; NLRP6 provides docking site to facilitate interaction between TAB2/3 and TRIM38 in RA synoviocytes in response to TNFalpha. (NLRP6 = ; TAB2/3 = transforming growth factor-b-activated kinase 1-binding protein 2/3; TRIM38 = tripartite motif 38) PMID: 28295271
    2. TRIM38 may act as a novel negative regulator for TLR3-mediated type I interferon signaling by targeting TRIF for degradation PMID: 23056470
    3. NF-kappaB is activated in response to TRIM38. PMID: 21789858
    4. Enterovirus 71 infection induces degradation of TRIM38. PMID: 21306652
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 10059

    KEGG: hsa:10475

    STRING: 9606.ENSP00000230099

    UniGene: Hs.584851