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TRAT1 Antibody

  • 货号：
    CSB-PA024235GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q6PIZ9
  • 基因名：
    TRAT1
  • 别名：
    HSPC062 antibody; pp29/30 antibody; T cell receptor interacting molecule antibody; T-cell receptor-associated transmembrane adapter 1 antibody; T-cell receptor-interacting molecule antibody; TCRIM antibody; TRAT1 antibody; TRAT1_HUMAN antibody; TRIM antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human TRAT1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
  • 基因功能参考文献：
    1. TRIM proteins trim the balance of homoeostasis by modulating various biological pathways through protein-protein interactions. PMID: 23969027
    2. MG53/TRIM72 protein can be directly applied as a therapeutic agent to increase membrane repair capacity of many cell types. PMID: 23699904
    3. TRIM acts to chaperone CTLA-4 transport to the cell surface; this function would be required to account for the phenotypic and functional properties of CD8(+) Tregs. PMID: 18817831
  • 亚细胞定位：
    Cell membrane; Single-pass type III membrane protein.
  • 组织特异性：
    Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level).
  • 数据库链接：

    HGNC: 30698

    OMIM: 604962

    KEGG: hsa:50852

    STRING: 9606.ENSP00000295756

    UniGene: Hs.138701