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TRAPPC11 Antibody

  • 货号：
    CSB-PA801799LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of U251 cells with CSB-PA801799LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TRAPPC11 Polyclonal antibody
  • Uniprot No.：
    Q7Z392
  • 基因名：
    TRAPPC11
  • 别名：
    TRAPPC11 antibody; C4orf41 antibody; Trafficking protein particle complex subunit 11 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Trafficking protein particle complex subunit 11 protein (704-836AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TRAPPC11 Antibody (CSB-PA801799LA01HU)，的标记方式是Non-conjugated。对于TRAPPC11 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA801799LB01HU TRAPPC11 Antibody, HRP conjugated ELISA
    FITC CSB-PA801799LC01HU TRAPPC11 Antibody, FITC conjugated
    Biotin CSB-PA801799LD01HU TRAPPC11 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
  • 基因功能参考文献：
    1. Recessive mutations in TRAPPC11 and GOSR2 are associated with congenital muscular dystrophy and hypoglycosylation of alpha-dystroglycan. PMID: 29855340
    2. The identified novel TRAPPC11 mutation represents an expansion of the myopathy phenotype described before and is characterised particularly by achalasia, alacrima, neurological and muscular phenotypes. PMID: 27707803
    3. TRAPPC11 role in protein glycosylation and lipid-linked oligosaccharides biosynthesis PMID: 26912795
    4. Homozygous mutations in the membrane trafficking component TRAPPC11 causes a form of autosomal-recessive, slowly progressive limb girdle muscular dystrophy with childhood onset and high serum creatine kinase. PMID: 23830518
  • 相关疾病：
    Limb-girdle muscular dystrophy 2S (LGMD2S)
  • 亚细胞定位：
    Golgi apparatus. Golgi apparatus, cis-Golgi network.
  • 蛋白家族：
    TRAPPC11 family
  • 数据库链接：

    HGNC: 25751

    OMIM: 614138

    KEGG: hsa:60684

    STRING: 9606.ENSP00000335371

    UniGene: Hs.443240