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  4. TRAFD1 Antibody

TRAFD1 Antibody

  • 货号：
    CSB-PA877646
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA877646(TRAFD1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA877646(TRAFD1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse spleen tissue, Primary antibody: CSB-PA877646(TRAFD1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 4 minutes
  • 其他：

产品详情

  • Uniprot No.：
    O14545
  • 基因名：
    TRAFD1
  • 别名：
    FLN29 antibody; FLN29 gene product antibody; Protein FLN29 antibody; TRAD1_HUMAN antibody; TRAF type zinc finger domain containing 1 antibody; TRAF type zinc finger domain containing protein 1 antibody; TRAF-type zinc finger domain-containing protein 1 antibody; TRAFD 1 antibody; TRAFD1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human TRAFD1
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.
  • 基因功能参考文献：
    1. FLN29 is a new negative feedback regulator of TLR signaling PMID: 16221674
    2. FLN29, in addition to playing a negative regulatory role in the TLR4 signaling pathway, negatively regulates the RIG-I-like helicase signaling pathway at the level of IPS-1/TRAF6 and IPS-1/TRAF3 complexes PMID: 18849341
  • 数据库链接：

    HGNC: 24808

    OMIM: 613197

    KEGG: hsa:10906

    STRING: 9606.ENSP00000257604

    UniGene: Hs.5148