TPST2 Antibody
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货号:CSB-PA024133LA01HU
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规格:¥440
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促销:
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图片:
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其他:
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) TPST2 Polyclonal antibody
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Uniprot No.:O60704
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基因名:TPST2
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别名:EC 2.8.2.20 antibody; Protein tyrosine sulfotransferase 2 antibody; Protein-tyrosine sulfotransferase 2 antibody; TANGO13B antibody; TPST-2 antibody; Tpst2 antibody; TPST2_HUMAN antibody; Transport and golgi organization 13 homolog B antibody; Tyrosylprotein phosphotransferase 2 antibody; Tyrosylprotein sulfotransferase 2 antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Protein-tyrosine sulfotransferase 2 protein (26-377AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
本页面中的产品,TPST2 Antibody (CSB-PA024133LA01HU),的标记方式是Non-conjugated。对于TPST2 Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA, IHC
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推荐稀释比:
Application Recommended Dilution IHC 1:20-1:200 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
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基因功能参考文献:
- Using a quantum mechanics protocol of alanine scanning, the study identified unequivocally the role of the amino acids involved in the TPST-2 catalytic mechanism. PMID: 26108987
- the first crystal structure of the human tyrosylprotein sulfotransferase isoform 2 complexed with a substrate peptide (C4P5Y3) derived from complement C4 and 3'-phosphoadenosine-5'-phosphate at 1.9 A resolution, is reported. PMID: 23481380
- The p.R153H variant was found in a family with hereditary pancreatitis; however, it did not segregate with the disease. PMID: 20460947
- Shear stress-dependent upregulation of TPST2 in human endothelium is mediated by a tyrosine kinase-dependent pathway PMID: 12056800
- Tyrosine sulfation of CCR5 N-terminal peptide follows a discrete pattern and temporal sequence PMID: 12169668
- The kinetic parameters of tyrosylprotein sulfotransferase-1 and -2, catalyzing tyrosine sulfation of CCR8 peptides, were determined using liquid chromatography electrospray ionisation mass spectrometry. PMID: 18672380
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亚细胞定位:Golgi apparatus membrane; Single-pass type II membrane protein.
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蛋白家族:Protein sulfotransferase family
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组织特异性:Widely expressed.
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数据库链接:
HGNC: 12021
OMIM: 603126
KEGG: hsa:8459
STRING: 9606.ENSP00000339813
UniGene: Hs.632768
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