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TOX2 Antibody

  • 货号：
    CSB-PA024074LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: K562 whole cell lysate, Raji whole cell lysate, Jurkat whole cell lysate
      All lanes: TOX2 antibody at 4.3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 52, 55, 50, 54 kDa
      Observed band size: 52, 50 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TOX2 Polyclonal antibody
  • Uniprot No.：
    Q96NM4
  • 基因名：
    TOX2
  • 别名：
    C20orf100 antibody; Chromosome 20 open reading frame 100 antibody; dJ1108D11.2 antibody; dJ495O3.1 antibody; GCX 1 antibody; GCX1 antibody; Granulosa cell HMG box protein 1 antibody; MGC15880 antibody; TOX high mobility group box family member 2 antibody; TOX2 antibody; TOX2_HUMAN antibody; Weakly similar to NONHISTONE CHROMOSOMAL PROTEIN 6A [S.cerevisiae] antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human TOX high mobility group box family member 2 protein (303-417AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TOX2 Antibody (CSB-PA024074LA01HU)，的标记方式是Non-conjugated。对于TOX2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA024074LB01HU TOX2 Antibody, HRP conjugated ELISA
    FITC CSB-PA024074LC01HU TOX2 Antibody, FITC conjugated
    Biotin CSB-PA024074LD01HU TOX2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Putative transcriptional activator involved in the hypothalamo-pituitary-gonadal system.
  • 基因功能参考文献：
    1. A haplotype block across a 24-kb region within the TOX2 gene reached genome-wide significance in haplotype-block-based regional heritability mapping. Single-SNP- and haplotype-based association tests demonstrated that five of nine genotyped SNPs and two haplotypes within this block were significantly associated with major depressive disorder. PMID: 28153336
    2. TOX2 plays a crucial role in controlling normal NK cell development by acting upstream of TBX21 transcriptional regulation PMID: 25352127
    3. A novel aberrantly hypermethylated CpG island in cancer was discovered within the TOX2 promoter. TOX2 was unmethylated in normal cells. Expression of two novel TOX2 transcripts was significantly reduced in primary lung tumors. PMID: 22496870
    4. Identification and functional analysis of the rat Gcx1 ortholog. PMID: 14764631
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 16095

    OMIM: 611163

    KEGG: hsa:84969

    UniGene: Hs.26608