Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. TMF1 Antibody

TMF1 Antibody

  • 货号：
    CSB-PA023904GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P82094
  • 基因名：
    TMF1
  • 别名：
    Androgen receptor coactivator 160 kDa protein antibody; Androgen receptor-associated protein of 160 kDa antibody; ARA160 antibody; TATA element modulatory factor 1 antibody; TATA element modulatory factor antibody; TMF antibody; Tmf1 antibody; TMF1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human TMF1-Specific
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP).
  • 基因功能参考文献：
    1. In patient with chronic granulomatous disease, a 5.8-kb, incomplete and partly exonized TMF1 transcript was identified in intron 1 of CYBB, in opposite orientation to the host gene. PMID: 24478191
    2. COG complex interacts with two different Rabs in addition to each end of the golgin "TATA element modulatory factor" (TMF). PMID: 23239882
    3. These observations suggest critical roles for TMF in two Rab6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the endoplasmic reticulum. PMID: 17698061
    4. Overexpression of TMF/ARA160 downregulates proangiogenic genes and attenuates the progression of prostate cancer xenografts. PMID: 19330832
  • 亚细胞定位：
    Cytoplasm. Nucleus. Golgi apparatus membrane. Note=Concentrated at the budding structures localized at the tips of cisternae.
  • 数据库链接：

    HGNC: 11870

    OMIM: 601126

    KEGG: hsa:7110

    STRING: 9606.ENSP00000381567

    UniGene: Hs.267632